Polynucleotides
Unlocking Radiant Skin.
Polynucleotides are biopolymers of nucleotide monomers. They are long chains of nucleotides, which are the building blocks of DNA and RNA. These molecules have various roles in the body, cellular repair and regeneration. In treatments, are used for their properties, helping to improve skin quality by promoting cell turnover and healing.
This treatment helps to stimulate natural regenerative processes, leading to skin texture, elasticity, and hydration.
It is also great for people who want to the signs of ageing on the skin.
What are Polynucleotides?
Polynucleotides are long chains of nucleotides, which are the building blocks of DNA and RNA. These molecules are derived from salmon DNA, which has been found to be highly biocompatible with human tissue.
The works at a cellular level to tissue repair, promote production, and improve skin .
Key benefits of Polynucleotides
Polynucleotides treatments offer for skin health and appearance:
Improved skin and tone
Reduction in fine lines and wrinkles
skin and elasticity
Brighter, more complexion
in and dark (particularly around the eyes)
Minimised appearance of scars and stretch marks
Overall skin rejuvenation
Polynucleotides Packages:
Per area: £350
Per area: £600
Per area: £850
FAQs
Which areas can be treated with ?
At Karwal Aesthetics, we offer for areas of the face and body:
Face: and lower face
Eyes: Under-eye area, crow’s feet, upper eyelids
Neck and décolletage: For crepey skin and horizontal lines
Hands: To improve skin and reduce visible signs of ageing
How many Polynucleotide Treatment are needed?
The number of treatments required varies on concerns and goals:
course: 2-4 spaced 2-4 weeks apart
Maintenance: every 6 months to results
Severe concerns: May more intensive treatment protocols
When will I see results from polynucleotides?
Results from Plinest treatments develop gradually:
Immediate: Some and subtle glow may be visible away
2-4 weeks: in skin texture and tone
4-8 weeks: More improvements as increases
3-6 months: results become apparent
Results typically last 6-12 months, depending on such as age, lifestyle, and skin condition.
Who is suitable for polynucleotides ?
are suitable for most adults looking to improve their skin quality. Ideal include those who:
Have early to moderate signs of ageing
Want fillers
Have or dehydrated skin
Are for anti-ageing treatments
Have realistic about results
Where do we offer polynucleotides?
We offer at our clinic in London Mayfair. Our is conveniently located in the heart of Mayfair, one of London’s most prestigious areas, making it easily for across the .
Clinic Location
Address: 15 Dover Street, London, W1S 4LP
Our clinic provides a and where you can receive your Plinest treatments from Dr Arun, an . The clinic is equipped with modern and adheres to the of safety and hygiene.
How to Find Us
By Underground: Green Park station (Jubilee, Piccadilly, and Victoria lines) is just a short walk away
By Bus: Multiple bus routes serve the Mayfair area
By Car: Limited street available; car parks nearby
To book your consultation or treatment, .
Improved Skin Texture: The treatment helps to smooth out fine lines and wrinkles, giving the skin a more texture.
Enhanced Elasticity: By boosting production, Eyes improves skin elasticity, making it more resilient and firm.
Increased Hydration: The polynucleotides help to moisture levels in the skin, preventing dryness and .
Natural-Looking Results: The properties of polynucleotides provide a subtle and enhancement, the overly look that some treatments can produce.
Minimal Downtime: Plinest Eyes is a invasive procedure with little to no downtime, individuals to resume their daily activities shortly after treatment.
What is the with ?
Notes for Sunekos, Profhilo & Plinest:
Needle entry points, redness, bruising, swelling and around injection sites immediately after is normal due to the very nature of the .
There may also be some tenderness present as the bruising and sets in. These symptoms will over the next 2-7 days, on your individual response to the treatment.
For 24 hours avoid:
Touching your face
Applying makeup
Skincare with active ingredients
No alcohol
No exercise
No hot showers or sauna/steam rooms
Both Plinest and Sunekos are bio-revitalisation treatments, but they differ in their composition and mechanisms of action. contains a of hyaluronic acid combined with a specific blend of amino acids, whilst Plinest uses derived from salmon DNA.
Key differences include:
Active ingredients: Sunekos relies on acid and amino acids to stimulate the extracellular matrix, whereas Plinest uses polynucleotides for regeneration and tissue repair.
Mechanism: Sunekos works by providing the building blocks for and synthesis, whilst Plinest actively fibroblast activity and has additional anti-inflammatory and antioxidant .
Treatment areas: Both can be used on similar areas, though Eye is specifically formulated for the periorbital region, whilst has different formulations (Sunekos 200 and Sunekos 1200) for varying levels of skin laxity.
Results: Both provide improvements. However, Sunekos is the preferred product at Karwal Aesthetics, more results and better in hyperpigmentation, fine lines, and skin texture—especially crepey skin.
vs.
Both Plinest and Profhilo are treatments that natural skin rejuvenation, but they differ in their and approach:
Active ingredients: Profhilo contains highly concentrated hyaluronic acid (HA), whilst uses polynucleotides from salmon DNA.
of action: works through bio-remodelling with HA to stimulate collagen and in four different types of collagen. Plinest works by directly fibroblast activity and has additional and properties.
Injection technique: uses the BAP (Bio Aesthetic Points) with 5 injection points per side of the face, whilst Plinest requires multiple injection points across the treatment area.
Spread: Profhilo’s unique formulation allows it to spread more easily under the skin after injection, whilst Plinest remains more localised to the sites.
vs. regeneration: primarily focuses on intense and bio-remodelling, whilst Plinest emphasises regeneration, tissue repair, and anti-inflammatory effects.
Treatment areas: Both can be used on similar areas, though is particularly noted for its and effects on the face and neck, whilst Plinest offers targeted like Plinest Eye for specific concerns.
Results: Both provide natural-looking . However, is the preferred at Karwal between the two. Profhilo a glow, plumpness, and to the skin.
Potential side
Plinest are generally well-tolerated, but some temporary side may occur:
Mild swelling at sites
Slight bruising (more common in areas)
or tenderness
Small bumps at injection points
These effects resolve within hours. Serious side are rare when performed by qualified practitioners.
Business Enquiries
Mayfair, London2nd Floor, 15 Dover Street, W1S 4LP
Closed
10: :00
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0% is available on all treatments from £500. Find out more by our Payment Plan page.
Please note: our clinic is on the second floor with stair access only.
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