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What is GLP-3 and How Does It Work? GLP-3 is a naturally occurring hormone in the body, derived from the proglucagon gene, primarily produced in the intestines. This peptide is a member of the incretin family, which promotes insulin secretion in response to meals. Unlike other incretins, GLP-3 has garnered interest due to its unique ability to enhance insulin sensitivity and regulate appetite more effectively. By binding to specific receptors on pancreatic beta cells, GLP-3 stimulates the secretion of insulin, especially in the presence of elevated blood glucose levels.
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