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CryoPen Cryotherapy
CryoPen™ is a state of the art treatment that uses extreme cold, or cryotherapy, to painlessly and safely unwanted, benign and superficial on the of the skin, such as warts, skin tags, verrucae, milia, cherry angiomas, scars, and resistant hyperpigmentation.
It has four main benefits over other treatments;
is and by a Belgian company, HO Equipment, and distributed in the United Kingdom by Cryosthetics (CryoskinCare Ltd). (In and Canada it is known as CryoProbe). It is used for in the of dermatology, podiatry, medical aesthetics and gynaecology/.
uses a referred to as cryotherapy – ‘cryo’ meaning ‘icy cold’. This involves the use of a high jet of oxide – N2O, (the source of the cold energy), which is directed at the specific lesion being treated, to within millimetre .
It is one of the leading lesion treatment available on the market to . The practitioner simply points the tip directly at the lesion and applies the . The jet of cold treats any abnormal tissue without interfering with or damaging normal tissue in a matter of seconds.
The CryoPen device is available in various different models – B, M and X which come with slightly applicators, and oxide cartridge capacity, but all achieve the same goal.
CryoPen B
The B model comes with one head for treating that are between 2 and 6mms wide and a 23.5g cartridge for the oxide gas, which has 300 seconds of flow. There is a B+ upgrade which features an additional, longer applicator head (60mm) for treating (genital or anal warts).
CyroPen M

The M model comes with two tips and an 8g oxide gas cartridge.
CryoPen X
The X model, which is the premium model, allows the use of a of four applicators for targeting treatment of benign lesions which are from a width of 1mm to 20mm (2 cm) or more, whilst causing no damage to the surrounding, healthy skin. This model also comes with capacity for two ampoule sizes for the oxide gas, depending on the size and type of lesion being and the amount of cryotherapy needed for maximum gas efficiency – the practitioner can choose from either an 8g or 16g cartridge which has a 100 second or 200 second gas flow respectively. There is also a X+ available with features two additional, longer heads (60mm and 120mm long) for condyloma.
therapy is a medical procedure that involves the application of nitrous oxide gas under high on to the skin. The gas is very cold which helps to freeze and destroy any benign lesions.
During the application, the tip of the CryoPen -89°C. The reason for this is to create a shock at the region where the gas is pointed by a rapid drop in temperatures. The drop has the effect of crystallising the fluid contents of the targeted cells, turning them into ice shards, resulting in the destruction of skin lesions as the surrounding the cells is ruptured and destroyed.
The of the cold is approximately 1mm per 5 seconds of treatment, so a 2mm sized lesion would take 10 seconds of nitrous oxide gas to treat.
During treatment, you may see a frost or on top of the lesion. This shouldn’t cause any worry as the frost usually goes away within a few seconds. A common technique called freeze-thaw-freeze can sometimes be used to freeze, then defrost a frozen lesion, and then freeze it again. Here, the frozen lesion is allowed to rest for 30 seconds and then a second whereby the tissue will freeze faster second time around and of the lesion is more .
After treatment, it is advisable to leave the area uncovered as this speeds up the healing . However, your may apply a simple dressing or if there is a chance that the lesion may get rubbed or aggravated in any way.
CryoPen is classed as, and CE mark certified, as a device.
The use of the CryoPen device to treat the full range of benign skin lesions can only be out by fully medical and those beauty therapists or aestheticians with an NVQ4 qualification or above.
Some of the lower models of the device may be used by with NVQ3 qualifications to treat a reduced range of benign lesions which they must be trained to treat, warts, milia, skin tags, verrucae, cherry and sun/liver spots.
treats benign skin lesions on the surface of the skin, many of which are no longer able to be by doctors under the NHS, due to their cosmetic nature. More complex lesions should be examined first and treated by a suitably qualified medical professional, so you may wish to speak to your GP about them first. It can treat on the face, scalp and body including:
• Skin tags
• Age/liver
•
• Cherry angioma
• Viral verrucae (warts)
• Solar (sun spots)
• Other pigmentation
• Plantar
• ( or anal warts)
• Popular nevi (moles, birthmarks etc)
• (water warts)
•
Treatment is safe for all (including and young adults, although you will need to check if the clinic is insured to treat minors).
data shows that the results are permanent after one or two . Some types of skin may return in other places if you are prone to such manifestations.
has been established to be very safe. However, be prepared for the following:
• Slight during the – As with most lesion treatments, you’ll feel some slight while is being applied. The discomfort usually feels like the pressure of a pen being against your skin. However, unless you have a problem such as a skin allergy, it will only last a few seconds. Generally, no topical anaesthesia (or cream) is required before .
• Mild stinging following the – Immediately after the procedure, you will likely experience mild to medium stinging that may last for several minutes to an hour. Again, don’t be too worried about the as it goes away naturally.
• Sores and – Rarely, the skin where the lesion was treated, usually becomes sore, red, weepy and . It may sting for an hour or so after . Often a scab will form in the following days. This is common where deep is used and may cause pain immediately after the . The practitioner may recommend topical or oral pain killers to relieve if required. It is important not to scratch or pick at a scab as this can lead to scarring.
The treated lesions should completely heal within 1 to 4 weeks and scabs formed around the lesion will shed after a week to 10 days. Lesions on the leg take the longest time to heal. Some people may a change in skin colour (pigmentation) or slight scarring in the treated area – change is more common in darker skin types and may not be temporary.
Hair can be damaged by cryotherapy so if the lesion is within an area of hair, such as on the scalp, then a small amount of hair loss may occur.
Rarely there is potential for superficial nerve damage, depending on the location of the lesion. This may cause a of numbness or tingling in the area which may last for a few months.
If a lesion does not heal as expected, or there is pain or redness after a few days, then you should contact the practitioner again as these could be signs of an infection.
Anyone who is otherwise can undergo a CryoPen .
However, there are a few cases:
• Firstly, it is that correct of a lesion is carried out before because some can be related to cancer and it is quite easy to confuse these with ordinary, benign lesions. So, the expert advice of a doctor or dermatologist is needed as CryoPen cannot be used to treat cancerous . If you are concerned about a lesion, or it has in any way recently, please speak to your GP as a first port of call.
• Secondly, CryoPen may not be used if the are too close to delicate of the body such as the eyes.
Treatment will not be advised for women or mothers, as the risks are unknown, and you will be advised to wait until after this period of time in your life before having treatment.
How long you need to apply the before seeing results often on the size and nature of the lesion. However, for a normal, superficial, benign lesion, it only takes 2 to 10 seconds to complete the procedure in one . Results are usually observable within1 to 6 weeks of .
4 weeks following treatment, OnabotulinumtoxinAAbobotulinumtoxinAIncobotulinumtoxinAPrabotulinumtoxinALetibotulinumtoxinARimabotulinumtoxinBHyaluronic Acid FillersCalcium Hydroxylapatite FillersPoly-L-lactic Acid FillersPolymethylmethacrylate FillersAutologous Fat GraftingForehead Lines TreatmentGlabellar Frown Lines TreatmentCrow’s Feet TreatmentBunny Lines TreatmentChemical Brow LiftLip FlipGummy Smile CorrectionMasseter ReductionJaw SlimmingDimpled Chin SmoothingCobblestone Chin SmoothingNefertiti Neck LiftMicro-BotoxMesotoxHyperhidrosis TreatmentChronic Migraine ReliefBruxism TreatmentTMJ TreatmentCervical Dystonia TreatmentNeck Spasm TreatmentBlepharospasm TreatmentLip AugmentationLip ContouringCheekbone EnhancementTear Trough FillersNasolabial Fold SofteningMarionette Line FillersLiquid RhinoplastyNon-Surgical Nose JobJawline ContouringJawline DefinitionChin AugmentationTemple VolumisingHand RejuvenationAcne Scar Subcision Filling a follow-up is usually recommended to assess the to treatment so the practitioner can determine if there is a need for additional treatments to completely remove any remaining lesions or parts of the lesion. In some cases, one treatment will and no follow-up is required for small, simple lesions.
However, if the lesion is too persistent and doesn’t go away following the initial treatment, a second can be done. This second should be done within 1 to 4 weeks of the first one.
Most benign lesions are with CryoPen for just £50, even if there are multiple, small lesions. If you have more than one similar lesion which is to be treated, then you may be charged an extra £25+, depending on the number and size of all the and the time needed. For example, warts and usually cost around £80.
These photos are real patients; your results may differ.

of keratosis: left – before and right – after 4 weeks

Treatment of wart on eyelid: left – before and right – after 4 weeks

Treatment of spot on cheek: left – before and right – after 3 weeks

Treatment of hemangioma: left – before and right – after 6 weeks
Photos courtesy of Dr Zois and Ho Equipments.
Video demonstrating the treatment of milia using the CryoPen
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All information within this site is researched and for accuracy of content. Please note that for prospective of treatments, information and guidance provided does not an in-depth with an experienced practitioner.